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Our findings suggest that prenatal exposure to OP pesticides, as measured by urinary DAP metabolites in women during is associated with poorer cognitive abilities in children at 7 years of age. Children in the highest quintile of maternal DAP concentrations had an average deficit of 7. 0 IQ points compared with those in the lowest quintile. Associations were linear, and we observed no threshold. Prenatal Exposure to Organophosphate Pesticides and IQ in 7 Year Old Children. Environmental Health Perspectives, 2011. Prospective cohort study of women and their children findings suggest that prenatal exposure to organophosphates is negatively associated with cognitive development, particularly perceptual reasoning, with evidence of effects beginning at 12 months and continuing through early childhood. Prenatal Exposure to Organophosphates, Paraoxonase 1, and Cognitive Development in Childhood. Environmental Health Perspectives, 2011. Prospective cohort study of an inner city population found that children with high levels of exposure to chlorpyrifos scored, on average, 6. 5 points lower on the Bayley Psychomotor Development Index and 3.
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